To have the right value of the possible causes responsible of muscles-skeleton disorders, and to have a right therapeutic measures, the Authors have get ready an holistic method, that value not only the damage's point, but also research in the others body-districts, named Peripheral Receptors, the causes responsible of pathologic manifestation. The methods is used on 61 VDU and it consists in: clinical rachis exam (like EPM methods), postural, odontological, oculistic, podiatric and psychologic visits. The study have permitted to underlines muscles-skeletons disorders precociously, not only in symptomatic subjects, but also in those asymptomatic, so it is an important prevention's instrument, diagnostic framing and medico-legal of studied pathologies.