Abstract
SPK-843 is a water-soluble antibiotic under co-development by Aparts and Kaken for the potential treatment of systemic fungal infections. By November 2004, SPK-843 was in phase II trials for systemic mycosis.
MeSH terms
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Animals
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Antifungal Agents / metabolism
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Antifungal Agents / pharmacokinetics
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Antifungal Agents / pharmacology*
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Antifungal Agents / therapeutic use*
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Antifungal Agents / toxicity*
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Clinical Trials, Phase I as Topic
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Clinical Trials, Phase II as Topic
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Humans
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Mycoses / drug therapy*
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Mycoses / microbiology
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Patents as Topic
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Polyenes / metabolism
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Polyenes / pharmacokinetics
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Polyenes / pharmacology*
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Polyenes / therapeutic use*
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Polyenes / toxicity*
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Structure-Activity Relationship
Substances
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Antifungal Agents
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Polyenes
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SPA S 843