Abstract
Indigin, alkylated xanthene (1) and indigoferic acid (2) have been isolated from the chloroform soluble fraction of Indigofera oblongifolia, along with beta-sitosterol (3) and 3-hydroxybenzoic acid (4), which are reported for the first time from this species. Their structures were determined through spectroscopic techniques. Both the new compounds 1 and 2 showed significant activity against enzyme lipoxygenase, while 2 further showed moderate inhibition against BChE.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Cholinesterase Inhibitors / isolation & purification
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Cholinesterase Inhibitors / pharmacology
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Cinnamates / isolation & purification*
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Cinnamates / pharmacology
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Fatty Acids / isolation & purification*
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Fatty Acids / pharmacology
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Hydroxybenzoates / isolation & purification
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Indigofera / chemistry*
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Inhibitory Concentration 50
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Lipoxygenase Inhibitors / isolation & purification*
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Lipoxygenase Inhibitors / pharmacology
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Magnetic Resonance Spectroscopy
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Plant Extracts / chemistry
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Sitosterols / isolation & purification
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Xanthenes / isolation & purification*
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Xanthenes / pharmacology
Substances
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Cholinesterase Inhibitors
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Cinnamates
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Fatty Acids
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Hydroxybenzoates
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Lipoxygenase Inhibitors
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Plant Extracts
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Sitosterols
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Xanthenes
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indigin
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indigoferic acid
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3-hydroxybenzoic acid
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gamma-sitosterol