Side-chain chiral centers of amino acid and helical-screw handedness of its peptides

Masakazu Tanaka; Kosuke Anan; Yosuke Demizu; Masaaki Kurihara; Mitsunobu Doi; Hiroshi Suemune

doi:10.1021/ja053842c

Side-chain chiral centers of amino acid and helical-screw handedness of its peptides

J Am Chem Soc. 2005 Aug 24;127(33):11570-1. doi: 10.1021/ja053842c.

Authors

Masakazu Tanaka¹, Kosuke Anan, Yosuke Demizu, Masaaki Kurihara, Mitsunobu Doi, Hiroshi Suemune

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. mtanaka@phar.kyushu-u.ac.jp

PMID: 16104711
DOI: 10.1021/ja053842c

Abstract

Both diastereomeric right-handed (P) and left-handed (M) 310-helices exist in homopeptides having twelve chiral centers at the side-chain bicyclic skeletons.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids / chemistry*
Crystallography, X-Ray
Models, Molecular
Molecular Conformation
Peptides / chemical synthesis
Peptides / chemistry*
Protein Structure, Secondary*

Substances

Amino Acids
Peptides