Gamma irradiation does not affect 7-day storage of platelet concentrates

Vox Sang. 2005 Aug;89(2):97-9. doi: 10.1111/j.1423-0410.2005.00647.x.

Abstract

Background and objectives: Extension of storage of leucocyte-reduced platelet concentrates (LR-PCs) to 7 days has recently been introduced, but the effect of gamma irradiation on in vitro parameters was unknown.

Materials and methods: A paired experiment was carried out, with gamma irradiation on day 1 or day 5 with 25 Gy, and no irradiation served as a reference.

Results: Measurements during storage up to 8 days after blood collection showed no significant differences of irradiated LR-PCs vs. the control.

Conclusions: Irradiation, either on day 1 or day 5, had no effect on platelet quality during a 7-day storage period.

MeSH terms

  • Blood Platelets / cytology*
  • Blood Platelets / radiation effects
  • Blood Preservation / methods*
  • Gamma Rays*
  • Humans
  • Leukocyte Reduction Procedures
  • Platelet Transfusion / instrumentation
  • Platelet Transfusion / methods
  • Specimen Handling
  • Time Factors