Prevention of neonatal sepsis

Clin Perinatol. 2005 Sep;32(3):601-15. doi: 10.1016/j.clp.2005.05.005.

Abstract

Neonatal sepsis is a leading infectious cause of infant mortality. While use of intrapartum antibiotic prophylaxis in the United States has led to dramatic declines in perinatal sepsis caused by the bacteria group B streptococcus, interventions to prevent perinatal sepsis due to other causes have not yet been clearly defined. This article synthesizes information on neonatal sepsis disease burden, trends, and risk factors and reviews current and potential approaches to neonatal sepsis prevention.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Antibiotic Prophylaxis*
  • Female
  • Humans
  • Incidence
  • Infant Mortality / trends
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology
  • Infant, Newborn, Diseases / microbiology
  • Infant, Newborn, Diseases / prevention & control*
  • Perinatal Care / methods
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / microbiology
  • Sepsis / epidemiology
  • Sepsis / microbiology
  • Sepsis / prevention & control*
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / prevention & control
  • Streptococcus agalactiae
  • United States / epidemiology

Substances

  • Anti-Bacterial Agents