Paroxysmal nocturnal hemoglobinuria

JNMA J Nepal Med Assoc. 2005 Jan-Mar;44(157):23-5.

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hemolytic disorder of acquired origin and is clinically manifested by chronic hemolysis, thromboses in various sites, and bone marrow failure. The disease is so rare that the delay in the diagnosis is not uncommon and this bears a tremendous impact on patient management. We present this case to draw attention to this uncommon cause of hemolytic anemia, which should be considered in any patient, of any age, who has signs of chronic hemolysis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Hemoglobinuria, Paroxysmal / complications
  • Hemoglobinuria, Paroxysmal / diagnosis*
  • Hemoglobinuria, Paroxysmal / therapy
  • Humans
  • Male