Daytime sleep latency in medication-matched Parkinsonian patients with and without sudden onset of sleep

Mov Disord. 2005 Dec;20(12):1620-2. doi: 10.1002/mds.20630.

Abstract

Currently, it is unclear whether sleep attacks in Parkinson's disease (PD) represent a novel entity or just a phenomenon of daytime sleepiness. We investigated 10 PD patients with sleep attacks and compared them with 10 PD patients without any daytime sleepiness. The patients were matched according to their dopaminergic medication and subjected to a sleep medical investigation. The mean sleep latency on the multiple sleep latency test was in the normal range and not significantly different between the groups. These data suggest that sleep attacks can occur against a background of normal alertness.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Case-Control Studies
  • Chi-Square Distribution
  • Disorders of Excessive Somnolence / drug therapy
  • Disorders of Excessive Somnolence / etiology*
  • Dopamine Agonists / therapeutic use
  • Female
  • Humans
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / drug therapy
  • Reaction Time / drug effects
  • Reaction Time / physiology*
  • Sleep Stages

Substances

  • Dopamine Agonists
  • Levodopa