Abstract
Oropharyngeal colonization by pathogenic gram-negative bacilli (GNB) and Staphylococcus aureus is associated with aspiration pneumonia. Decolonization in high-risk populations may be important. We prospectively evaluated six antiseptic compounds in nasogastric tube-fed frail elderly patients; only polymixine reduced oropharyngeal colonization with GNB. None had an effect on S. aureus colonization.
MeSH terms
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / administration & dosage*
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Colony Count, Microbial
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Enteral Nutrition*
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Female
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Gram-Negative Bacteria / drug effects*
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Gram-Negative Bacteria / growth & development
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Gram-Negative Bacteria / pathogenicity
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Gram-Negative Bacterial Infections / microbiology
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Humans
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Intubation, Gastrointestinal
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Male
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Middle Aged
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Oropharynx / microbiology*
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / growth & development
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Staphylococcus aureus / pathogenicity