BlastXtract--a new way of exploring translated searches

Bioinformatics. 2005 Sep 15;21(18):3667-8. doi: 10.1093/bioinformatics/bti598. Epub 2005 Jul 26.

Abstract

Summary: Searches of translated, unannotated genomic DNA sequences against protein databases is a useful early-stage method for discovering protein homologues encoded by the sequence, but generates huge amounts of output data that quickly become impregnable. BlastXtract is a web-based tool for managing and visualizing results from large translated BLAST and FastA searches. It combines the speed and storage benefits of relational database management systems with an easy-to-use graphical navigation map, and greatly facilitates the early exploration of genomic sequence.

Availability: BlastXtract can be downloaded from http://bioinfo.ucc.ie/blastxtract/.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Bifidobacterium / genetics
  • Computational Biology / instrumentation
  • Computational Biology / methods*
  • Computer Graphics
  • DNA / metabolism
  • Database Management Systems*
  • Databases, Genetic*
  • Databases, Nucleic Acid*
  • Databases, Protein
  • Genome
  • Lactobacillus / genetics
  • Sequence Alignment
  • Sequence Analysis
  • Sequence Analysis, DNA
  • Software
  • Statistics as Topic / methods

Substances

  • DNA