Benzothieno and benzofurano annelated estranes

Steroids. 2005 Dec 1;70(13):856-66. doi: 10.1016/j.steroids.2005.06.001. Epub 2005 Jul 19.

Abstract

The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry
  • Benzofurans / chemistry
  • Catalysis
  • Cyclization
  • Estranes / chemical synthesis*
  • Estranes / chemistry
  • Molecular Structure

Substances

  • Azo Compounds
  • Benzofurans
  • Estranes
  • benzofuran