Abstract
2,2-dimethyl cyclopentanones are readily prepared by acid catalyzed ring expansion of isopropenylcyclobutanols; the method allows ready access to the family of sesquiterpenes cuparanes and herbertanes, as demonstrated by the synthesis of (+/-)-alpha-cuparenone and the direct precursor of (+/-)-herbertene.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acids / chemistry*
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Catalysis
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Cyclopentanes / chemical synthesis
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Cyclopentanes / chemistry*
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Methylation
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Molecular Structure
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Sesquiterpenes / chemical synthesis*
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Sesquiterpenes / chemistry
Substances
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Acids
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Cyclopentanes
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Sesquiterpenes
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alpha-cuparenone
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herbertene
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cyclopentanone