Dihydrostilbene derivatives from Glycyrrhiza glabra leaves

J Nat Prod. 2005 Jul;68(7):1099-102. doi: 10.1021/np050034q.

Abstract

Four new dihydrostilbenes, alpha,alpha'-dihydro-3,5-dihydroxy-4'-acetoxy-5'-isopentenylstilbene (1), alpha,alpha'-dihydro-3,3',4'-trihydroxy-5-O-isopentenyl-6-isopentenylstilbene (2), alpha,alpha'-dihydro-3,5,3'-trihydroxy-4'-methoxystilbene (3), and alpha,alpha'-dihydro-3,3'-dihydroxy-5beta-d-O-glucopyranosyloxy-4'-methoxystilbene (4), together with seven known flavonoids, glabranin isomer, naringenin, lupiwighteone, pinocembrin 7-O-glucoside, astragalin, isoquercitrin, vicenin II, and the inositol, pinitol, were isolated from the leaves of Glycyrrhiza glabra grown in Sicily. The structures of 1-4 were elucidated by spectroscopic methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apigenin / chemistry
  • Apigenin / isolation & purification*
  • Flavanones / chemistry
  • Flavanones / isolation & purification
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glycyrrhiza / chemistry*
  • Italy
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Stilbenes / chemistry
  • Stilbenes / isolation & purification*

Substances

  • Flavanones
  • Glucosides
  • Stilbenes
  • apigenin-6,8-di-C-glycopyranoside
  • Apigenin
  • naringenin