Viability of a random pattern dorsal skin flap, in diabetic rats

Acta Cir Bras. 2005 May-Jun;20(3):225-8. doi: 10.1590/s0102-86502005000300006.

Abstract

Purpose: Evaluation of the viability of a random pattern dorsal skin flap, in rats with experimentally induced diabetes mellitus.

Methods: Thirty adult, male, Wistar EPM rats were distributed, at random, in two groups: I--Control (flap elevation) and II--Experimental (flap elevation ten days after alloxan induced diabetes).

Results: The mean areas of necrosis in the different groups were 36.4% (Control) and 52.1% (Experimental).

Conclusion: The random pattern dorsal skin flap was less viable in the diabetic rats.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alloxan
  • Animals
  • Diabetes Mellitus, Experimental / chemically induced
  • Diabetes Mellitus, Experimental / physiopathology*
  • Male
  • Necrosis / physiopathology
  • Rats
  • Rats, Wistar
  • Surgical Flaps / pathology*
  • Tissue Survival / physiology*

Substances

  • Alloxan