Granulocytic sarcoma presenting as tumors of the cervix

Gynecol Oncol. 2005 Sep;98(3):493-7. doi: 10.1016/j.ygyno.2005.04.028.

Abstract

Background: Granulocytic sarcoma of the cervix, leading to the diagnosis of acute myelogenous leukemia (AML), is a rare event.

Case: A 33-year-old woman presented with vaginal bleeding, pain, and a large pelvic mass involving the cervix, extending bilaterally to the pelvic side walls. A biopsy of the cervix revealed granulocytic sarcoma, and a subsequent bone marrow biopsy confirmed the diagnosis of AML.

Results: The majority of patients with cervical granulocytic sarcoma present with vaginal bleeding, sometimes with abdominal pain and other systemic symptoms. The overall 2-year survival rates for all patients with granulocytic sarcoma in the literature is 6%, and none of the patients lived 5 years.

Conclusion: Granulocytic sarcoma of the cervix is rare. Awareness of this entity will allow earlier diagnosis and appropriate treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis*
  • Sarcoma, Myeloid / diagnosis*
  • Uterine Cervical Neoplasms / diagnosis*