A preliminary study of the patterns of Sin Nombre viral infection and shedding in naturally infected deer mice (Peromyscus maniculatus)

Vector Borne Zoonotic Dis. 2005 Summer;5(2):127-32. doi: 10.1089/vbz.2005.5.127.

Abstract

Deer mice (Peromyscus maniculatus) were trapped in southern Manitoba, Canada and tested for evidence of Sin Nombre virus infection. Viral genome was amplified from tissues as well as saliva/oropharyngeal fluid, and urine samples were collected from seropositive animals. Detection of viral RNA in tissue samples and excreta/secreta from mice suggest that differences may exist between naturally infected rodents with respect to viral shedding.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Female
  • Gene Amplification
  • Hantavirus Pulmonary Syndrome / epidemiology
  • Hantavirus Pulmonary Syndrome / transmission
  • Hantavirus Pulmonary Syndrome / veterinary*
  • Male
  • Manitoba / epidemiology
  • Oropharynx / virology
  • Peromyscus / virology*
  • RNA, Viral / analysis
  • RNA, Viral / blood
  • RNA, Viral / urine
  • Reverse Transcriptase Polymerase Chain Reaction / veterinary
  • Rodent Diseases / epidemiology*
  • Rodent Diseases / transmission
  • Rodent Diseases / virology
  • Sin Nombre virus / genetics
  • Sin Nombre virus / immunology
  • Sin Nombre virus / isolation & purification*
  • Virus Shedding*

Substances

  • Antibodies, Viral
  • RNA, Viral