Pediatric central nervous system infections and inflammatory white matter disease

Mary T Silvia; Daniel J Licht

doi:10.1016/j.pcl.2005.03.003

Pediatric central nervous system infections and inflammatory white matter disease

Pediatr Clin North Am. 2005 Aug;52(4):1107-26, ix. doi: 10.1016/j.pcl.2005.03.003.

Authors

Mary T Silvia¹, Daniel J Licht

Affiliation

¹ Division of Neurology, The Children's Hospital of Philadelphia, 34th & Civic Center Boulevard, Philadelphia, PA 19104, USA.

PMID: 16009259
DOI: 10.1016/j.pcl.2005.03.003

Abstract

This article reviews the immunology of the central nervous system and the clinical presentation, diagnosis, and treatment of children with viral or parainfectious encephalitis. The emphasis is on the early recognition of treatable causes of viral encephalitis (herpes simplex virus), and the diagnosis and treatment of acute disseminated encephalomyelitis are described in detail. Laboratory and imaging findings in the two conditions also are described.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Central Nervous System / immunology
Central Nervous System Viral Diseases / diagnosis*
Central Nervous System Viral Diseases / therapy*
Child
Child, Preschool
Diagnosis, Differential
Encephalitis, Viral / diagnosis
Encephalitis, Viral / therapy
Encephalomyelitis, Acute Disseminated / diagnosis
Encephalomyelitis, Acute Disseminated / therapy
Humans
Infant
Infant, Newborn
Magnetic Resonance Imaging
Prognosis