Lanostane triterpenoids from the inedible mushroom Fomitopsis spraguei

Dang Ngoc Quang; Yuuki Arakawa; Toshihiro Hashimoto; Yoshinori Asakawa

doi:10.1016/j.phytochem.2005.05.020

Lanostane triterpenoids from the inedible mushroom Fomitopsis spraguei

Phytochemistry. 2005 Jul;66(14):1656-61. doi: 10.1016/j.phytochem.2005.05.020.

Authors

Dang Ngoc Quang¹, Yuuki Arakawa, Toshihiro Hashimoto, Yoshinori Asakawa

Affiliation

¹ Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.

PMID: 16002106
DOI: 10.1016/j.phytochem.2005.05.020

Abstract

Investigation of the methanolic extract of the inedible mushroom Fomitopsis spraguei (Polyporaceae) led to the isolation of five lanostane-type triterpenoids (1-5): three new compounds named fomitopsins A-C (2-4), and two known compounds, quercinic acid C (1) and 3alpha-carboxyacetyl-12beta-hydroxyquercinic acid (5). Their structures were determined by 2D NMR, MS, IR, UV spectra, and X-ray crystallographic analyses. An X-ray crystal structure analysis of quercinic acid C (1) established its stereochemistry as 3R,12R-dihydroxy-24R-methyl-23-oxo-25S-lanost-8-en-26-oic acid.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Agaricales / chemistry*
Models, Molecular
Molecular Structure
Triterpenes / chemistry*
Triterpenes / isolation & purification

Substances

Triterpenes