S(O)-pixyl protecting group as efficient mass-tag

Pablo L Bernad Jr; Safraz Khan; Vladimir A Korshun; Edwin M Southern; Mikhail S Shchepinov

doi:10.1039/b504913j

S(O)-pixyl protecting group as efficient mass-tag

Chem Commun (Camb). 2005 Jul 21:(27):3466-8. doi: 10.1039/b504913j. Epub 2005 Jun 9.

Authors

Pablo L Bernad Jr¹, Safraz Khan, Vladimir A Korshun, Edwin M Southern, Mikhail S Shchepinov

Affiliation

¹ Tridend Technologies (a Division of OGT), Hirsch Building, Begbroke Business & Science Park, Sandy Lane, Yarnton, Oxford UK OX5 1PF.

PMID: 15997299
DOI: 10.1039/b504913j

Abstract

We report herein the design, preparation and first applications of novel trityl tags with adjustable stability, efficient as protecting groups or MS analytes.

MeSH terms

Genomics*
Indicators and Reagents / chemical synthesis
Indicators and Reagents / chemistry
Mass Spectrometry*
Oligonucleotides / chemistry*
Trityl Compounds / chemical synthesis
Trityl Compounds / chemistry*

Substances

Indicators and Reagents
Oligonucleotides
Trityl Compounds