Abstract
We report on a Subsaharian patient with HIV infection and disseminated tuberculosis who developed acute, severe hypersensitivity reaction to efavirenz including acute renal failure in addition to liver and lung involvement, in the absence of skin changes or blood eosinophilia.
MeSH terms
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Acute Kidney Injury / chemically induced*
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Adenine / administration & dosage
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Adenine / analogs & derivatives
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Adult
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Alkynes
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Anti-HIV Agents / administration & dosage
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Anti-HIV Agents / adverse effects*
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Benzoxazines / adverse effects*
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Cyclopropanes
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Drug Hypersensitivity / complications*
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Ghana / ethnology
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HIV
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HIV Infections / complications*
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HIV Infections / drug therapy
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HIV Protease Inhibitors / administration & dosage
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Humans
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Lamivudine / administration & dosage
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Male
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Mycobacterium tuberculosis / isolation & purification
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Organophosphonates / administration & dosage
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Reverse Transcriptase Inhibitors / administration & dosage
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Reverse Transcriptase Inhibitors / adverse effects*
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Ritonavir / administration & dosage
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Tenofovir
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Tuberculosis / complications
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Tuberculosis / diagnosis
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Tuberculosis / drug therapy
Substances
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Alkynes
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Anti-HIV Agents
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Benzoxazines
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Cyclopropanes
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HIV Protease Inhibitors
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Organophosphonates
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Reverse Transcriptase Inhibitors
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Lamivudine
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Tenofovir
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Adenine
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efavirenz
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Ritonavir