MAPK pathway activation in colorectal cancer: a therapeutic opportunity for GRP receptor antagonists

Lancet Oncol. 2005 Jul;6(7):444-5. doi: 10.1016/S1470-2045(05)70226-6.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Bombesin / analogs & derivatives
  • Bombesin / pharmacology
  • Colorectal Neoplasms / metabolism*
  • Drug Delivery Systems
  • Humans
  • MAP Kinase Signaling System / drug effects*
  • Peptide Fragments / pharmacology
  • Rats
  • Receptors, Bombesin / antagonists & inhibitors
  • Receptors, Bombesin / drug effects*
  • Receptors, Bombesin / physiology

Substances

  • Antineoplastic Agents
  • Peptide Fragments
  • Receptors, Bombesin
  • bombesin (6-14), Tpi(6)-Leu(13)-psi(CH2NH)-Leu(14)-
  • Bombesin