Rh(I)-catalyzed CO gas-free cyclohydrocarbonylation of alkynes with formaldehyde to alpha,beta-butenolides

Chem Commun (Camb). 2005 Jul 14:(26):3295-7. doi: 10.1039/b503816b. Epub 2005 Jun 1.

Abstract

The rhodium(I)-catalyzed reaction of alkynes with formaldehyde proceeds via the double incorporation of a carbonyl moiety from formaldehyde, resulting in a CO gas-free cyclohydrocarbonylation leading to alpha,beta-butenolides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives*
  • 4-Butyrolactone / chemical synthesis
  • 4-Butyrolactone / chemistry
  • Alkynes / chemistry*
  • Carbon Monoxide / chemistry*
  • Catalysis
  • Cyclization
  • Formaldehyde / chemistry*
  • Molecular Structure
  • Rhodium / chemistry*
  • Stereoisomerism

Substances

  • Alkynes
  • Formaldehyde
  • Carbon Monoxide
  • butenolide
  • Rhodium
  • 4-Butyrolactone