MINER: software for phylogenetic motif identification

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W267-70. doi: 10.1093/nar/gki465.

Abstract

MINER is web-based software for phylogenetic motif (PM) identification. PMs are sequence regions (fragments) that conserve the overall familial phylogeny. PMs have been shown to correspond to a wide variety of catalytic regions, substrate-binding sites and protein interfaces, making them ideal functional site predictions. The MINER output provides an intuitive interface for interactive PM sequence analysis and structural visualization. The web implementation of MINER is freely available at http://www.pmap.csupomona.edu/MINER/. Source code is available to the academic community on request.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Motifs*
  • Conserved Sequence
  • Internet
  • Models, Molecular
  • Phylogeny*
  • Protein Conformation
  • Proteins / chemistry
  • Proteins / classification
  • Sequence Alignment / methods*
  • Sequence Analysis, Protein / methods*
  • Software*
  • User-Computer Interface

Substances

  • Proteins