Insertions in the human immunodeficiency virus type 1 protease and reverse transcriptase genes: clinical impact and molecular mechanisms

Antimicrob Agents Chemother. 2005 Jul;49(7):2575-82. doi: 10.1128/AAC.49.7.2575-2582.2005.

Authors

Mark A Winters¹, Thomas C Merigan

Affiliation

¹ Division of Infectious Diseases and Geographic Medicine, Stanford University, 300 Pasteur Drive, Room S-146, Stanford, California 94305-5107, USA. mark.winters@stanford.edu

No abstract available

Publication types

Review

MeSH terms

Amino Acid Substitution*
Anti-HIV Agents / pharmacology
Anti-HIV Agents / therapeutic use
Drug Resistance, Viral*
HIV Infections / drug therapy*
HIV Infections / virology
HIV Protease / genetics*
HIV Reverse Transcriptase / genetics*
HIV-1 / drug effects*
HIV-1 / enzymology
HIV-1 / genetics
Humans
Microbial Sensitivity Tests
Models, Molecular
Reverse Transcriptase Inhibitors / pharmacology
Reverse Transcriptase Inhibitors / therapeutic use
Treatment Failure

Substances

Anti-HIV Agents
Reverse Transcriptase Inhibitors
HIV Reverse Transcriptase
HIV Protease