ent-Verticillane-type diterpenoids from the Japanese liverwort Jackiella javanica

Fumihiro Nagashima; Katsuhiro Kishi; Yuko Hamada; Shigeru Takaoka; Yoshinori Asakawa

doi:10.1016/j.phytochem.2005.05.012

ent-Verticillane-type diterpenoids from the Japanese liverwort Jackiella javanica

Phytochemistry. 2005 Jul;66(14):1662-70. doi: 10.1016/j.phytochem.2005.05.012.

Authors

Fumihiro Nagashima¹, Katsuhiro Kishi, Yuko Hamada, Shigeru Takaoka, Yoshinori Asakawa

Affiliation

¹ Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-Cho, Tokushima 770-8514, Japan. fnaga@ph.bunri-u.ac.jp

PMID: 15978642
DOI: 10.1016/j.phytochem.2005.05.012

Abstract

Three ent-verticillane diterpenoids and two ent-sesquiterpenoids were isolated from the Japanese liverwort Jackiella javanica Schiffn. together with five known ent-verticillane and three ent-kaurane diterpenoids, and three sesquiterpenoids. Five ent-verticillane epoxides were synthetically prepared from ent-verticillols action to clarify the absolute configuration of natural ent-9,10-epoxyverticillol. Their structures were established by extensive NMR spectroscopic and X-ray crystallographic analyses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diterpenes / chemistry*
Diterpenes / isolation & purification
Hepatophyta / chemistry*
Japan
Models, Molecular
Molecular Structure

Substances

Diterpenes