[Effect of rarely repeated immobilization episodes on hypoxia-tolerance and anxiogenic stress severity]

V E Tseĭlikman; I A Volchegorskiĭ; O B Tseĭlikman; N V Bubnov; A I Sinitskiĭ; E I L'vovskaia; O N Bliumental'

[Effect of rarely repeated immobilization episodes on hypoxia-tolerance and anxiogenic stress severity]

Ross Fiziol Zh Im I M Sechenova. 2005 Apr;91(4):394-9.

[Article in Russian]

Authors

V E Tseĭlikman, I A Volchegorskiĭ, O B Tseĭlikman, N V Bubnov, A I Sinitskiĭ, E I L'vovskaia, O N Bliumental'

PMID: 15969439

Abstract

4 episodes of immobilization stress (60 minutes, once 72 hours) led to diminution of hypoxia tolerance and anxiety-depressive disorders of behavior. The later shifts were associated with decrease of IL-4 concentration and simultaneous increase of IL-6 level in blood serum. The stress-induced behavioral shifts appeared to correlate with IL-4 concentration in blood of stress-sustained rats.

MeSH terms

Anaerobiosis
Animals
Anxiety / blood
Anxiety / etiology*
Behavior, Animal / physiology*
Hypoxia / etiology*
Interleukin-4 / blood*
Interleukin-4 / metabolism
Interleukin-6 / blood
Interleukin-6 / metabolism
Rats
Restraint, Physical
Stress, Psychological / blood
Stress, Psychological / etiology

Substances

Interleukin-6
Interleukin-4