Evidence of cerebral reorganization following perinatal stroke demonstrated with fMRI and DTI tractography

Samantha L Heller; Linda A Heier; Richard Watts; Theodore H Schwartz; Natalie Zelenko; Werner Doyle; Orrin Devinsky

doi:10.1016/j.clinimag.2004.09.003

Evidence of cerebral reorganization following perinatal stroke demonstrated with fMRI and DTI tractography

Clin Imaging. 2005 Jul-Aug;29(4):283-7. doi: 10.1016/j.clinimag.2004.09.003.

Authors

Samantha L Heller¹, Linda A Heier, Richard Watts, Theodore H Schwartz, Natalie Zelenko, Werner Doyle, Orrin Devinsky

Affiliation

¹ Weill Cornell Medical College, United States.

PMID: 15967322
DOI: 10.1016/j.clinimag.2004.09.003

Abstract

A 44-year-old man with a left perinatal stroke and recurrent refractory epilepsy underwent functional MRI (fMRI) for motor and language mapping to determine if further epilepsy surgery could be performed without loss of language. Language was activated excessively in the right hemisphere, with only small areas of left hemisphere activation. This suggests bilateral language dominance acquired secondary to the perinatal stroke with the right hemisphere activation resulting from neonatal neuronal reorganization. Functional data were overlaid onto 3D diffusion tensor tractography, providing a unique image of the right hemisphere language recruitment.

Publication types

Case Reports

MeSH terms

Adult
Brain Mapping / methods*
Cerebral Cortex / physiopathology*
Diffusion Magnetic Resonance Imaging*
Dominance, Cerebral*
Epilepsy / physiopathology
Humans
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Language*
Magnetic Resonance Imaging*
Male
Neuronal Plasticity
Stroke / physiopathology*