Circadian clocks: translation

Curr Biol. 2005 Jun 21;15(12):R470-3. doi: 10.1016/j.cub.2005.06.014.

Abstract

One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Circadian Rhythm / physiology*
  • Circadian Rhythm Signaling Peptides and Proteins
  • Gene Expression Regulation
  • Humans
  • Phosphorylation
  • Synechococcus / physiology*

Substances

  • Bacterial Proteins
  • Circadian Rhythm Signaling Peptides and Proteins
  • KaiA protein, cyanobacteria
  • KaiC protein, cyanobacteria