Trauma and resulting sensitization effects are modulated by psychological factors

Psychoneuroendocrinology. 2005 Nov;30(10):965-73. doi: 10.1016/j.psyneuen.2005.04.012.

Abstract

Traumas have both immediate consequences and proactive consequences. Examples include learned helplessness, HPA-axis responsivity, gastrointestinal vulnerability to ulcer, and other correlates of anxiety disorders. Both immediate and proactive consequences may be modulated by behavioral and cognitive evolutionary evolved adaption processes, among which are forms of learning that enable 'coping'. Examples of associative and non-associative forms of coping and effects on learned helplessness, HPA-axis responsivity, and gastrointestinal vulnerability are presented. The importance of attention to behavioral contingencies in situations in which potentially traumatic events occur is emphasized as critical to understanding that it is not the physical event(s) per se that determine the immediate and long term consequences.

Publication types

  • Review

MeSH terms

  • Adaptation, Psychological / physiology
  • Adrenal Cortex Hormones / physiology
  • Animals
  • Helplessness, Learned
  • Humans
  • Stomach Ulcer / etiology
  • Wounds and Injuries / complications*
  • Wounds and Injuries / pathology
  • Wounds and Injuries / psychology*

Substances

  • Adrenal Cortex Hormones