[Induction of anaesthesia with target-controlled inhalation of sevoflurane in adults with the ZEUS anaesthesia machine]

Ann Fr Anesth Reanim. 2005 Jul;24(7):802-6. doi: 10.1016/j.annfar.2005.04.029.
[Article in French]

Abstract

Objectives: To evaluate if the new anaesthesia platform ZEUS (Dräger Medical) allows the induction of anaesthesia with target-controlled inhalation of sevoflurane.

Study design: Prospective clinical study.

Patients: Adult ASA I or II patients scheduled for elective surgery under general anaesthesia.

Methods: After preoxygenation during 3 min at 100% oxygen, patients were asked to breathe normally; the target end-tidal concentration of sevoflurane was fixed at 4% without priming of the circuit. Sufentanil (target concentration 0.5 ng/ml) was administered 40 s after.

Results: Ten patients (48+/-22 yrs) were included. Sevoflurane was detected in the circuit after 36+/-5 s; the target end-tidal concentration of sevoflurane was obtained at 130+/-19 s. Loss of consciousness was observed after 119+/-7 s. The induction was achieved in all patients without any incident.

Conclusion: This new anaesthesia system make available the induction of anaesthesia with sevoflurane without priming of the circuit.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Anesthesia, Inhalation / adverse effects
  • Anesthesia, Inhalation / instrumentation*
  • Anesthesiology / instrumentation*
  • Anesthetics, Inhalation / administration & dosage*
  • Anesthetics, Inhalation / adverse effects
  • Drug Delivery Systems
  • Female
  • Hemodynamics / physiology
  • Humans
  • Male
  • Methyl Ethers / administration & dosage*
  • Methyl Ethers / adverse effects
  • Middle Aged
  • Monitoring, Intraoperative
  • Preanesthetic Medication
  • Sevoflurane

Substances

  • Anesthetics, Inhalation
  • Methyl Ethers
  • Sevoflurane