Abstract
Many clinical trials have been conducted to prevent cardiovascular complications and reduce mortality in hypertensive patients. Undoubted, but limited effects of beta-blocker and diuretic antihypertensive drugs had been established. Although angiotensin-converting enzyme inhibitor and angiotensin II receptor antagonist lowered the incidence of events and mortality less than classical antihypertensive drugs, recent studies revealed that prompt and enough lowering the blood pressure is more important than choosing the types of drugs.
MeSH terms
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Adrenergic beta-Antagonists / therapeutic use
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Aged
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Amlodipine / therapeutic use
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Angiotensin II Type 1 Receptor Blockers / therapeutic use
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Angiotensin-Converting Enzyme Inhibitors / therapeutic use
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Calcium Channel Blockers / therapeutic use
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Coronary Disease / drug therapy*
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Coronary Disease / etiology*
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Coronary Disease / prevention & control
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Diuretics / therapeutic use
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Double-Blind Method
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Drug Therapy, Combination
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Enalapril / therapeutic use
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Humans
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Hypertension / complications*
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Hypertension / drug therapy*
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Losartan / therapeutic use
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Randomized Controlled Trials as Topic*
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Treatment Outcome
Substances
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Adrenergic beta-Antagonists
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Angiotensin II Type 1 Receptor Blockers
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Angiotensin-Converting Enzyme Inhibitors
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Calcium Channel Blockers
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Diuretics
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Amlodipine
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Enalapril
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Losartan