EEG changes caused by the tonic squeezing of the distal joint of the little finger of both hands were investigated on 12 healthy volunteers, age 20-56 (average 35.5). Pain stimulation applied to the right hand was stronger than that applied to the left. Power spectra was measured in 7 EEG ranges: delta--2-4, theta1--4-6, theta2--6-8, alpha1--8-10.5, alpha2--10.5-13, beta1--13-20 and beta2--20-35 Hz. The increase of power in the different areas of the cerebral cortex was a dominant effect of pain influence in beta1 and beta2 as well as in both alpha-ranges. The pain stimulation influenced EEG-parameters bilaterally. It was supposed that increment of alpha-synchronization during peripheral pain reflected the inhibition processes in the thalamo-cortical system. This process most likely limited the area of afferent activation in the cortex. The topography of the significant power changes in alpha1- and alpha2-ranges was different during strong pain as well as after its cessation. Different parameters of functional brain activity during pain stimulation seemed to be reflected in alpha1- and alpha2-rhythms. The significant increment of spectral power in alpha-, beta- and theta2-ranges was demonstrated after cessation of strong pain in comparison to the pre-pain condition. Thus, the changes in EEG parameters reflect the latent and inertial character of the pain effects.