Abstract
The protective layer of the epidermis in Drosophila (cuticle) and mice (stratum corneum) are structurally unrelated. Yet new evidence suggests a conserved transcription factor, Grainyhead, controls both their development and the means by which both structures repair themselves.
MeSH terms
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Animals
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DNA-Binding Proteins / metabolism*
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Dopa Decarboxylase / metabolism
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Drosophila / genetics
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Drosophila / physiology*
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Drosophila Proteins
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Epidermis / growth & development*
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Gene Expression Regulation*
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Mice / genetics
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Mice / physiology*
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Nuclear Proteins
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Signal Transduction / physiology*
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Transcription Factors / metabolism*
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Tyrosine 3-Monooxygenase / metabolism
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Wound Healing / genetics
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Wound Healing / physiology*
Substances
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DNA-Binding Proteins
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Drosophila Proteins
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ELF1 protein, human
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Elf1 protein, mouse
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Nuclear Proteins
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Transcription Factors
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grh protein, Drosophila
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Tyrosine 3-Monooxygenase
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Dopa Decarboxylase