Abstract
A lycoctonine-type norditerpenoid alkaloid, swatinine (1), along with four known norditerpenoid alkaloids, delphatine (3), lappaconitine (4), puberanine (5), and N-acetylsepaconitine (6), and were isolated from the aerial parts of Aconitum laeve Royle. Compound 2 has been isolated for the first time from a natural source. The structure of compound 1 was deduced on the basis of spectral data. The anti-inflammatory, antioxidant and tyrosinase inhibition studies on all six compounds have also been carried out.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aconitum / chemistry*
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Alkaloids / chemistry*
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Alkaloids / pharmacology*
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Anti-Inflammatory Agents / chemistry*
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Anti-Inflammatory Agents / pharmacology
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Antioxidants / chemistry*
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Antioxidants / pharmacology
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Free Radicals
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Humans
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In Vitro Techniques
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Models, Molecular
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Molecular Structure
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Monophenol Monooxygenase / antagonists & inhibitors*
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Plant Components, Aerial / chemistry
Substances
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Alkaloids
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Anti-Inflammatory Agents
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Antioxidants
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Free Radicals
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Monophenol Monooxygenase