Sequence analysis of near full-length HIV type 1 subtype D primary strains isolated in Cape Town, South Africa, from 1984 to 1986

AIDS Res Hum Retroviruses. 2005 May;21(5):410-3. doi: 10.1089/aid.2005.21.410.

Abstract

South Africa has one of the fastest growing HIV-1 epidemics worldwide, consisting mostly of subtype C. However, HIV-1 subtype B and subtype D viruses were isolated in the beginning of the epidemic in the early 1980s. This study describes the amplification, cloning, and near full-length genome sequencing of four HIV-1 subtype D primary strains, isolated from 1984 to 1986 in Cape Town, in what seems to have been a small restricted subtype D epidemic in the country.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Outbreaks*
  • Genome, Viral*
  • HIV Infections / epidemiology*
  • HIV Infections / virology
  • HIV-1 / classification*
  • HIV-1 / genetics
  • Humans
  • Male
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Analysis, DNA*
  • South Africa / epidemiology

Associated data

  • GENBANK/AY773338
  • GENBANK/AY773339
  • GENBANK/AY773340
  • GENBANK/AY773341