Optical fiber-based on-line UV/Vis spectroscopic monitoring of chemical reaction kinetics under high pressure in a capillary microreactor

Fernando Benito-Lopez; Willem Verboom; Masaya Kakuta; J Han G E Gardeniers; Richard J M Egberink; Edwin R Oosterbroek; Albert van den Berg; David N Reinhoudt

doi:10.1039/b500429b

Optical fiber-based on-line UV/Vis spectroscopic monitoring of chemical reaction kinetics under high pressure in a capillary microreactor

Chem Commun (Camb). 2005 Jun 14:(22):2857-9. doi: 10.1039/b500429b. Epub 2005 Apr 22.

Authors

Fernando Benito-Lopez¹, Willem Verboom, Masaya Kakuta, J Han G E Gardeniers, Richard J M Egberink, Edwin R Oosterbroek, Albert van den Berg, David N Reinhoudt

Affiliation

¹ Laboratory of Supramolecular Chemistry and Technology (SMCT), MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede, The Netherlands.

PMID: 15928782
DOI: 10.1039/b500429b

Abstract

With a miniaturized (3 microL volume) fiber-optics based system for on-line measurement by UV/Vis spectroscopy, the reaction rate constants (at different pressures) and the activation volumes (deltaV(not =)) were determined for a nucleophilic aromatic substitution and an aza Diels-Alder reaction in a capillary microreactor.