This study re-evaluated the effectiveness of the anti-drink driving and anti-speeding enforcement and publicity campaigns implemented in the Australian State of Victoria which have thus far yielded mixed results in several evaluations. As opposed to previous evaluations, this study focused on the effects of these campaigns on young male drivers who formed the primary target and examined the combined effects of the campaigns on the total number of serious crashes. Our results showed that the anti-drink driving enforcement and publicity campaigns had a significant independent effect in reducing crashes but their interactive effect was anti-complementary. Conversely, the anti-speeding enforcement and publicity campaigns had no independent effect but their interactive effect was significant in reducing serious crashes involving young male drivers.