Photoselective vaporization of the prostate: the basel experience after 108 procedures

Eur Urol. 2005 Jun;47(6):798-804. doi: 10.1016/j.eururo.2005.02.003. Epub 2005 Mar 2.

Abstract

Objectives: This study aims to investigate safety and efficacy of 80 watt high-power potassium titanyl phosphate (KTP) laser vaporization of the prostate in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).

Methods: 108 patients underwent 80W KTP laser vaporization. Functional follow-up included measurement of maximum urinary flow rate (Qmax), postvoid residual volume (Vres) and International Prostate Symptom Score (IPSS) within a 12 months period.

Results: The average prostate volume was 52.2+/-24.3 ml and the preoperative PSA value was 3.6+/-3.6 ng/dl. Mean operation time was 54.5+/-25.0 min. Qmax increased highly significantly (p<0.001) by 111% (+7.9 ml/s) at discharge, 212% (+15.1 ml/s) after three months, 201% (+14.3 ml/s) after six months and 252% (+17.9 ml/s) after 12 months. Correspondingly, Vres, IPSS and Bother Score improved to an extent that was statistically highly significant (p<0.001) immediately after surgery. The observed complication rate within one year was low.

Conclusions: 80 W KTP laser vaporization is a virtually bloodless, safe and effective procedure for surgical treatment of LUTS secondary to BPH. A significant improvement of objective and subjective voiding parameters was observed just after surgery. KTP laser vaporization is associated with a low rate of complications.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Follow-Up Studies
  • Humans
  • Laser Therapy*
  • Male
  • Middle Aged
  • Phosphates
  • Prostatic Hyperplasia / complications
  • Prostatic Hyperplasia / surgery*
  • Retrospective Studies
  • Safety
  • Titanium
  • Treatment Outcome
  • Urination Disorders / etiology
  • Urination Disorders / physiopathology
  • Urination Disorders / surgery
  • Urodynamics
  • Urologic Diseases

Substances

  • Phosphates
  • potassium titanylphosphate
  • Titanium