Cinnamylphenols from Phyllodium pulchellum

Chien-Chang Shen; Shr-Ting Wang; Show-Yinn Tsai; Hui-Chuan Yang; Bor-Jinn Shieh; Chien-Chih Chen

doi:10.1021/np049599x

Cinnamylphenols from Phyllodium pulchellum

J Nat Prod. 2005 May;68(5):791-3. doi: 10.1021/np049599x.

Authors

Chien-Chang Shen¹, Shr-Ting Wang, Show-Yinn Tsai, Hui-Chuan Yang, Bor-Jinn Shieh, Chien-Chih Chen

Affiliation

¹ National Research Institute of Chinese Medicine, No. 155-1, Sec. 2, Li Nung Street, Peitou, Taipei, Taiwan, Republic of China.

PMID: 15921433
DOI: 10.1021/np049599x

Abstract

Four new cinnamylphenols, pulchelstyrenes A (1), B (2), C (3), and D (4), together with citrusinol, yukovanol, methyl piperitol, and 4-hydroxy-2,3-dimethoxybenzaldehyde were isolated from the aerial part of Phyllodium pulchellum. The structures of these compounds were determined by spectroscopic methods. Compounds 2, 3, and citrusinol exhibited marginal cytotoxicity against KB cells, and citrusinol also showed mild cytotoxicity against the HepG2 cell line.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / isolation & purification*
Antineoplastic Agents, Phytogenic / pharmacology
Drug Screening Assays, Antitumor
Fabaceae / chemistry*
Humans
KB Cells
Molecular Structure
Phenols / chemistry
Phenols / isolation & purification*
Phenols / pharmacology
Plants, Medicinal / chemistry*
Taiwan
Tumor Cells, Cultured

Substances

Antineoplastic Agents, Phytogenic
Phenols