Dermoscopic features of eruptive melanocytic naevi in an adult patient receiving immunosuppressive therapy for Crohn's disease

Melanoma Res. 2005 Jun;15(3):223-4. doi: 10.1097/00008390-200506000-00014.

Abstract

The induction of multiple eruptive melanocytic naevi has frequently been reported to occur in association with chemotherapy or immunosuppressive regimens, particularly in children and adolescents. We describe the dermoscopic features of eruptive melanocytic naevi in an adult non-transplanted patient receiving immunosuppressive therapy for Crohn's disease. By dermoscopy, we observed a peripheral rim of large brown globules in most of the lesions. We have previously identified a group of patients characterized by this dermoscopic feature. These patients were children, adolescents and young adults with renal allografts receiving immunosuppressive therapy. The findings of our case strongly suggest that this dermoscopic feature may be associated with eruptive naevi developed in association with immunosuppression from any cause.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Azathioprine / adverse effects*
  • Crohn Disease / therapy
  • Dermoscopy
  • Female
  • Humans
  • Immunosuppression Therapy / adverse effects
  • Immunosuppressive Agents / adverse effects*
  • Nevus, Pigmented / etiology*
  • Nevus, Pigmented / pathology
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / pathology

Substances

  • Immunosuppressive Agents
  • Azathioprine