Identification of CTX-M-14 {beta}-lactamase in a Salmonella enterica serovar enteritidis isolate from Japan

Hidemasa Izumiya; Kadumi Mori; Masato Higashide; Kazumichi Tamura; Nobuko Takai; Kenji Hirose; Jun Terajima; Haruo Watanabe

doi:10.1128/AAC.49.6.2568-2570.2005

Identification of CTX-M-14 {beta}-lactamase in a Salmonella enterica serovar enteritidis isolate from Japan

Antimicrob Agents Chemother. 2005 Jun;49(6):2568-70. doi: 10.1128/AAC.49.6.2568-2570.2005.

Authors

Hidemasa Izumiya¹, Kadumi Mori, Masato Higashide, Kazumichi Tamura, Nobuko Takai, Kenji Hirose, Jun Terajima, Haruo Watanabe

Affiliation

¹ Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan. izumiya@nih.go.jp

Abstract

We analyzed the resistance to cefotaxime of a Salmonella enterica serovar Enteritidis isolate from a stool culture of a 4-year-old boy. It produced a beta-lactamase CTX-M-14, encoded by two related R plasmids. The region surrounding the blaCTX-M-14 gene had an original mosaic structure containing insertion sequences (IS26 and IS903D).

MeSH terms

Anti-Bacterial Agents / pharmacology*
Cefotaxime / pharmacology*
Cephalosporin Resistance / genetics*
Child, Preschool
Feces / microbiology
Humans
Japan
Male
Microbial Sensitivity Tests
Molecular Sequence Data
R Factors / genetics
Salmonella Infections
Salmonella enteritidis / drug effects
Salmonella enteritidis / enzymology*
Sequence Analysis, DNA
beta-Lactamases / genetics
beta-Lactamases / metabolism*

Substances

Anti-Bacterial Agents
beta-lactamase CTX-M-14
beta-Lactamases
Cefotaxime

Associated data

GENBANK/AB180674