Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy

Proc Natl Acad Sci U S A. 2005 May 31;102(22):7781-2. doi: 10.1073/pnas.0503261102. Epub 2005 May 23.
No abstract available

Publication types

  • Comment

MeSH terms

  • Cell Differentiation*
  • Diabetes Mellitus, Type 1 / therapy*
  • Genetic Engineering*
  • Genetic Therapy / methods*
  • Hepatocytes / cytology*
  • Homeodomain Proteins / genetics*
  • Humans
  • Islets of Langerhans / cytology*
  • Trans-Activators / genetics*
  • Transduction, Genetic / methods

Substances

  • Homeodomain Proteins
  • Trans-Activators
  • pancreatic and duodenal homeobox 1 protein