Silencing Bcl-X(L) in cancer therapy

Cancer Biol Ther. 2005 Apr;4(4):398-9. doi: 10.4161/cbt.4.4.1761. Epub 2005 Apr 27.
No abstract available

Publication types

  • Comment

MeSH terms

  • Apoptosis / drug effects*
  • Apoptosis Regulatory Proteins / pharmacology*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Cell Survival / drug effects
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / genetics
  • Colonic Neoplasms / metabolism
  • Colonic Neoplasms / pathology
  • Cytochromes c / metabolism
  • Cytosol
  • Down-Regulation / drug effects
  • Drug Resistance, Neoplasm
  • Drug Synergism
  • Female
  • Humans
  • Ligands
  • Membrane Glycoproteins / pharmacology*
  • Mitochondria / metabolism
  • Ovarian Neoplasms / drug therapy*
  • Ovarian Neoplasms / genetics
  • Ovarian Neoplasms / metabolism
  • Ovarian Neoplasms / pathology
  • RNA, Small Interfering / metabolism*
  • RNA, Small Interfering / pharmacology
  • TNF-Related Apoptosis-Inducing Ligand
  • Tumor Necrosis Factor-alpha / pharmacology*
  • bcl-X Protein / metabolism*

Substances

  • Apoptosis Regulatory Proteins
  • Ligands
  • Membrane Glycoproteins
  • RNA, Small Interfering
  • TNF-Related Apoptosis-Inducing Ligand
  • TNFSF10 protein, human
  • Tumor Necrosis Factor-alpha
  • bcl-X Protein
  • Cytochromes c