Titanium-mediated alkylative coupling of N-acylpyrroles

Org Lett. 2005 May 26;7(11):2105-8. doi: 10.1021/ol050352g.

Abstract

[reaction: see text]. Inter- and intramolecular titanium-mediated coupling reactions of N-acylpyrroles are reported for convenient functionalization of terminal olefins. Comparison with the Kulinkovich reaction of esters and other carboxylic acid derivatives is also included.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkenes / chemistry
  • Alkylation
  • Catalysis
  • Indicators and Reagents
  • Molecular Structure
  • Pyrroles / chemical synthesis*
  • Pyrroles / chemistry*
  • Titanium / chemistry*

Substances

  • Alkenes
  • Indicators and Reagents
  • Pyrroles
  • Titanium