Circadian clocks are seeing the systems biology light

Genome Biol. 2005;6(5):219. doi: 10.1186/gb-2005-6-5-219. Epub 2005 Apr 28.

Abstract

Circadian rhythms are those biological rhythms that have a periodicity of around 24 hours. Recently, the generation of a circadian transcriptional network -- compiled from RNA-expression and promoter-element analysis and phase information -- has led to a better understanding of the gene-expression patterns that regulate the precise 24-hour clock.

Publication types

  • Review

MeSH terms

  • Animals
  • Circadian Rhythm / genetics*
  • Feedback, Physiological
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Mammals / genetics
  • Models, Genetic
  • Promoter Regions, Genetic / genetics
  • RNA / metabolism
  • Regulatory Elements, Transcriptional*
  • Systems Biology*

Substances

  • RNA