Additional dose constraints for analytical beam weighting optimization in IMRT

Radiother Oncol. 2005 May;75(2):224-6. doi: 10.1016/j.radonc.2005.03.014.

Abstract

This work presents an improvement to an algorithm for analytical beam weighting optimization where a flexible objective function, which considers 'importance factors' for each anatomical region and 'allowed deviations' from the prescribed dose, is defined. This upgrading allows forcing the mean value of the dose distribution to be the desired value, by using Lagrange multipliers. A real case is presented to show the effect of this change.

MeSH terms

  • Algorithms*
  • Dose Fractionation, Radiation
  • Humans
  • Models, Theoretical*
  • Neoplasms / radiotherapy
  • Radiotherapy / methods*