Islet isolation and transplantation from an annular pancreas: a case report

JOP. 2005 May 10;6(3):274-6.

Abstract

Context: Annular pancreas is an uncommon congenital anomaly formed by a thin band of normal pancreatic tissue encircling the duodenum.

Case report: We report the first case of an islet isolation and transplantation from an annular pancreas. The pancreas together with duodenum was procured from a 32-year-old previously healthy man after diagnosis of brain death. The pancreas including the annular portion was distended well after intraductal collagenase perfusion. A total of 276,064 islet equivalent was recovered and transplanted into a type 1 diabetic patient.

Conclusions: Bearing in mind the shortage of donors, patients with this anomalous condition should not be excluded as potential organ donors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Death
  • Cell Separation*
  • Diabetes Mellitus, Type 1 / surgery
  • Duodenum / anatomy & histology
  • Humans
  • Islets of Langerhans / cytology*
  • Islets of Langerhans Transplantation*
  • Male
  • Pancreas / abnormalities*
  • Tissue and Organ Procurement