Metal ions as cofactors for the binding of inhibitors to methionine aminopeptidase: a critical view of the relevance of in vitro metalloenzyme assays

Angew Chem Int Ed Engl. 2005 Jun 6;44(23):3620-3. doi: 10.1002/anie.200500592.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminopeptidases / antagonists & inhibitors
  • Aminopeptidases / chemistry*
  • Binding Sites
  • Cations, Divalent / chemistry
  • Cobalt / chemistry
  • Coenzymes / chemistry
  • Escherichia coli Proteins / antagonists & inhibitors
  • Escherichia coli Proteins / chemistry*
  • Metalloendopeptidases / antagonists & inhibitors
  • Metalloendopeptidases / chemistry*
  • Methionyl Aminopeptidases
  • Protease Inhibitors / chemistry*
  • Pyridones / chemistry
  • Thiabendazole / chemistry

Substances

  • Cations, Divalent
  • Coenzymes
  • Escherichia coli Proteins
  • Protease Inhibitors
  • Pyridones
  • Cobalt
  • Aminopeptidases
  • Methionyl Aminopeptidases
  • Metalloendopeptidases
  • Thiabendazole

Associated data

  • PDB/1YVM