The first case of septicemia due to nontoxigenic Corynebacterium diphtheriae in Poland: case report

Ann Clin Microbiol Antimicrob. 2005 May 5:4:8. doi: 10.1186/1476-0711-4-8.

Abstract

Background: Toxigenic strains of Corynebacterium diphtheriae are well known agent of diphtheria. Nontoxigenic strains can cause atypical course of the disease. Invasive diseases caused by C. diphtheriae occur very rare.

Case presentation: We have described the first case of septicemia and endocarditis due to nontoxigenic C. diphtheriae biotype gravis in Poland. The patient has not belonged to any group of risk such infection.

Conclusion: The case presented in this article shows unusual case of infection connected with nontoxigenic C. diphtheriae that took place in the area where have been no cases of diphtheria and other C. diphtheriae infections for near ten years. It shows the importance of identifying Corynebacterium isolates at the species level especially when the strain has been isolated from normally sterile sites.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bacteremia / etiology*
  • Corynebacterium diphtheriae / drug effects
  • Corynebacterium diphtheriae / isolation & purification*
  • Endocarditis, Bacterial / etiology*
  • Humans
  • Male
  • Microbial Sensitivity Tests