Zinc supplementation: neuroprotective or neurotoxic?

Nutr Rev. 2005 Apr;63(4):122-5. doi: 10.1111/j.1753-4887.2005.tb00130.x.

Abstract

While zinc is essential for normal brain function and repair, recent work has implicated this trace element in the neuronal damage and death that follow traumatic brain injury, stroke, and seizure. Therefore, the development of new zinc-based therapeutic strategies will need to consider the emerging roles of zinc in the central nervous system.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain Diseases / metabolism
  • Central Nervous System / drug effects
  • Central Nervous System / metabolism*
  • Dietary Supplements
  • Humans
  • Neuroprotective Agents / administration & dosage*
  • Neuroprotective Agents / metabolism
  • Neurotoxins / administration & dosage*
  • Neurotoxins / metabolism
  • Zinc / administration & dosage*
  • Zinc / metabolism*

Substances

  • Neuroprotective Agents
  • Neurotoxins
  • Zinc